Stability of protein molecules.
نویسندگان
چکیده
منابع مشابه
Regulating protein stability in mammalian cells using small molecules.
Regulating protein stability using small molecules provides a rapid, reversible, and tunable method to study a protein of interest’s (POI) role in cells. We recently designed a small protein domain based on the 12-kDa FKBP (FK506 binding protein) that can be fused at either the carboxyl or amino terminus of a protein of interest. This destabilization domain (DD) confers instability to fusion pr...
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Estimation of protein stability is important for many reasons: first providing an understanding of the basic thermodynamics of the process of folding, protein engineering, and protein stability plays important role in biotechnology especially in food and protein drug design. Today, proteins are used in many branches, including industrial processes, pharmaceutical industry, and medical fields. A...
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We present a simple proof of the stability of the hydrogen molecule (MMmm). It does not rely on the proton-to-electron mass ratio M/m being very large, and actually holds for arbitrary values of M/m. Some asymmetric molecules of the type (m+1 m + 2 m − 3 m − 4 ) are also stable. Possible applications to molecules containing antiparticles and to exotic hadrons in the quark model are briefly outl...
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Using a modified atomic force microscope (AFM), individual double-stranded (ds) DNA molecules attached to an AFM tip and a gold surface were overstretched, and the mechanical stability of the DNA double helix was investigated. In lambda-phage DNA the previously reported B-S transition at 65 piconewtons (pN) is followed by a second conformational transition, during which the DNA double helix mel...
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ژورنال
عنوان ژورنال: Nihon Kessho Gakkaishi
سال: 1987
ISSN: 0369-4585,1884-5576
DOI: 10.5940/jcrsj.29.5